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For five years I went through hell and back to become a Mummy! I had three miscarriages from natural pregnancies, five IUI attempts, five IVF attempts, and three operations to remove endometriosis, a polyp and a fibroid. I have been with my 'almost perfect' Husband since 2003. We married in 2009 on Valentine's Day and we are extremely happy together. I decided to start a blog because I needed to write down my thoughts and feelings to show myself and others how I was never going to give up until we got our forever baby.

Since having my baby, I'm inspired to create: Baby Blankets by Me & Mum

Wednesday 15 February 2012

Uterine Natural Killer Cells - Results

I had an email from Professor Quenby:


NK results: My team and I have studied your endometrium very thoroughly.
 We have found that the following changes have occurred: your glands have developed normally, your stromal cells appear to be developing normally, blood vessels are appearing normally and the epithelial surface looks normal. These changes mean that ovulation occurred, as did the post ovulation rise in oestrogen and progesterone and that these hormones had the desired effect on your endometrium. Your NK count was 6.9% of your stromal cells.
The upper limit of normal is 5%. This result was high.

I then spoke to the Prof this evening and we discussed the results and treatment. The treatment is basically 20mg steroids from the day of the positive pregnancy test, up to 12weeks. Her team have found that using progesterone and steroids together works better. So I have three possible scenarios:

TTC Naturally - use progesterone from 7DPO and take the steroid as soon as you get even a faint line on the test. If not pregnant stop the progesterone.

TTC IUI - take the progesterone and steroids from a positive pregnancy test.

TTC IVF - progesterone is from EC and steroid from ET.

What does this all mean to me? I'm not really affected by the outcome if I'm being honest because nothing matters but getting pregnant, only then does the fact that I have high uNkcells come into play. If I'm not pregnant it doesn't matter. However, it could be a reason for my first two miscarriages and could possibly explain why IVF hasn't worked - especially IVF #3 when we had a good blasto put back but it didn't work.

The Prof also said once I am Pg I can ring up the clinic and she will scan me every two weeks, from 6weeks. So I'm happy about that!

So I just need to get pregnant now! I really want to do another round of IVF but we can't afford to for a while, so onto IUI #5 when AF arrives! Fingers crossed!

1 comment:

  1. Hello,

    This is the perfect blog for anyone who wants to know about Natural killer cells. These cells play a major role in the rejection of tumors and cells infected by viruses. They kill cells by releasing small cytoplasmic granules of proteins called perforin and granzyme that cause the target cell to die by apoptosis. Thanks a lot for sharing this...

    Contract Research

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